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Cytokines are signaling molecules released by cells into the circulation to induce and/or modulate an immune response. Immune cells produce large amounts of cytokines, such as interleukins and interferons, to respond to perturbations such as tumors. IL-2 (interleukin-2) and IFN-α (interferon-alpha) are two FDA-approved cytokines used to treat melanoma.1 Additional information on immunotherapy can be found in our resource center here.
1. T.A. Waldmann, "Cytokines in Cancer Immunotherapy," Cold Spring Harb Perspect Biol, 2017.
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