ZAP-70 Antigen

Zap-70, a Syk family protein tyrosine kinase expressed in T and NK cells, plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement. Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues, presumably by two mechanisms: autophosphorylation and transphosphorylation by the Src family tyrosine kinase, Lck. Tyrosine phosphorylation of Zap-70 correlates with its increased kinase activity and downstream signaling events.


 Clone: SBZAP  Isotype: IgG1 Mouse

The monoclonal antibody SBZAP was generated against a KLH-peptide sequence corresponding to the human ZAP-70 amino acid residues 280-309.
 

Choose a ZAP-70 Model

Product Line Specifications

Формат Liquid
Specificity ZAP-70
Form PE
Clone SBZAP
Isotype IgG1 Mouse
Target Species Human
Flow Product Line IOTest
Item Specifications Referenced B57658

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


Техническая документация