TCR Vβ11 Antigen
TCR Vβ11 is also called TCRBV11S1. Vβ11 is the human variable β11 chain of the T cell receptor. Two Vβ11 sequences are described, PL3.12 and PH15. These sequences differ only in their leader sequence and therefore lead to the same mature protein. An invariant Vα24/Vβ11 T cell receptor is expressed in all individuals by clonal expanded CD4– CD8– T cells, reactive to bacterial antigens. This unique lymphocyte population restricted by the CD1d molecule recognition has been identified as the natural killer T (NKT) cells. Vβ11 is expressed by 0.4% to 0.9% of peripheral CD3+ cells in normal blood. This sequence is also referred to as TRBV25-1 (based on the IMGT gene nomenclature).
|Clone: C21||Isotype: IgG2a Mouse|
|The C21 recognizes the gene product of PL3.12 and PH15 sequences. The specificity of this antibody has been confirmed at the First Human TcR Monoclonal Antibody Workshop in San Francisco in 1995.|
Product Line Specifications
|Flow Product Line||IOTest|
|Item Specifications Referenced||IM2290|
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.