IgE (Dε2) Antigen

The anti-IgE mAb binds to circulating IgE as well as to IgE antibodies bound to the low affinity receptor FcεRII (expressed mainly on eosinophils, B lymphocytes), or to the high affinity receptor FcεRI (expressed on mast cells, basophils, monocytes and monocytes-derived cells). The anti-IgE antibody induces the histamine release from basophils. However, it is known in the literature information that basophils from 10% to 20% of donors completely fail to release histamine in response to anti-IgE, designated anti-IgE "non releasers".


 Clone: E124.2.8  Isotype: IgG1 Mouse

The E124.2.8 monoclonal antibody binds specifically to the Dε2 constant domain of human Immunoglobulin E (IgE) (Dε2 is the heat labile region of IgE).
 

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Product Line Specifications

Формат Freeze-dried
Specificity IgE (Dε2)
Form UNLB
Clone E124.2.8
Isotype IgG1 Mouse
Target Species Human
Item Specifications Referenced A40174

The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent. 


Техническая документация