The CD79a molecule (MB-1, Igα) is part of the MB-1/B29 (CD79a/CD79b) disulfide-linked heterodimer which is non-covalently associated with membrane immunoglobulins (Igs) to build the B Cell antigen Receptor (BCR) complex. CD79a is a 40-45 kDa glycoprotein and belongs to the Ig superfamily of surface antigens. CD79a protein is specifically and strictly expressed throughout B lymphocyte differentiation. It appears early in ontogeny, probably before expression of cytoplasmic μ-chain, and is present in the cytoplasm of plasma cells.
|Clone: HM47||Isotype: IgG1 Mouse|
|The HM47 antibody is recommended to be used in flow cytometry after permeabilization with saponin-based permeabilization reagent IntraPrep. The HM47 antibody reacts with a cytoplasmic epitope of the CD79a molecule.|
Product Line Specifications
|Cross Reactivity||Cynomolgus Monkey, Indian Rhesus, Chimpanzee, Olive Baboon|
|Flow Product Line||IOTest|
|Item Specifications Referenced||B42018|
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.