CD35 Antigen
The CD35 antigen is a polymorphic molecule. Different molecular weights: 160, 190, 220, 250 and 285 kDa were reported for the various allotypes. It is known as the complement receptor type I (CR1) with affinity for C3b, C4b and iC3b. The CD35 antigen is expressed by granulocytes (except basophils), B lymphocytes, a subset of T-cells, monocytes, some NK cells, erythrocytes macrophages cultured in vitro, glomerular podocytes and follicular dendritic cells. The CD35 antigen mediates phagocytosis by neutrophils and monocytes of complement coated particles.
| Clone: J3D3 | Isotype: IgG1 Mouse |
| The J3D3 monoclonal antibody inhibits CR1-mediated decay of cells bound to the alternative and classical pathways to C3-convertase sites. It also inhibits C3b dependent rosette formation with lymphocytes. | |
Choose a CD35 Model
Product Line Specifications
| Формат | Liquid |
| Specificity | CD35 |
| Form | FITC |
| Clone | J3D3 |
| Isotype | IgG1 Mouse |
| Target Species | Human |
| Flow Product Line | IOTest |
| Item Specifications Referenced | IM1836 |
The specifications above are not representative of all reagents but only to the item/part number referenced in this Product Line Specifications table. Please view a product's detail page to view all product specifications for that particular reagent.